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Epiberberine chloride

Glpbio
Catalog No:GC35996-10mM (in 1mL DMSO) CAS No.:889665-86-5 MDLNo: Brand:Glpbio purity: 特性: Purpose:Epiberberine chloride 是从黄连中得到的生物碱,为有效的 AChE 和 BChE 抑制剂,和非竞争性的 BACE1 抑制剂,IC50 值分别为 1.07,6.03 和 8.55 μM。Epiberberine chloride 具有抗氧化作用,能够清除 ONOO- (IC50,16.83 μM),对阿尔滋海默症和糖尿病有潜在治疗作用。在 3T3-L1 细胞分化早期,Epiberberine chloride 能够下调 Raf/MEK1/2/ERK1/2 和 AMPKα/Akt 信号通路。DMSO: 7.4 mg/mL (19.90 mM)
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